The Effects of Coffee Consumption and Green Coffee Supplementation on Clinical and Metabolic Outcomes in Polycystic Ovary Syndrome: A Systematic Review

Putu Ayuning Dinda Nirmalayanthi, I Kadek Suardina

Abstract


 

 Polycystic ovary syndrome (PCOS) is a common endocrine-metabolic disorder affecting women of reproductive age and is associated with insulin resistance, hyperandrogenism, and dyslipidemia. Bioactive compounds in coffee, such as caffeine and chlorogenic acid, may have potential benefits in improving these conditions. Objective: This systematic review aimed to evaluate the effects of coffee consumption and green coffee extract supplementation on clinical and metabolic outcomes in women with PCOS. A systematic literature search was conducted in Scopus, Web of Science, PubMed, and Google Scholar. Studies meeting the PICOS inclusion criteria were selected and analyzed using a narrative synthesis approach. A total of 5 studies were included, comprising 3 randomized controlled trials and 2 case-control studies. Observational studies demonstrated an inverse association between coffee consumption and the risk of PCOS. Green coffee extract supplementation showed improvements in lipid profiles, reductions in androgen levels, and increased antioxidant capacity. However, no significant effects were observed on glycemic, anthropometric, or inflammatory parameters. Coffee consumption and supplementation with green coffee extract may offer potential benefits in the management of PCOS, particularly in improving metabolic and hormonal parameters. However, further well-designed studies are required to confirm their effectiveness. 

Keywords: Polycystic ovary syndrome, coffee consumption, green coffee extract, chlorogenic acid, metabolic outcomes, hormonal parameters 


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References


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DOI: https://doi.org/10.18585/ijbcs.v1i3.32

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